Estradiol Test FAQ
What is an Estradiol Test?
Why is an Estradiol Test important?
Why is an Estradiol Test level important in women?
Why is an Estradiol Test level important in men?
What type of specimen will I submit?
Do I need to fast to take this test?
How long does it take to get test results?
Accesa Labs does not provide medical advice, diagnosis or treatment. All users should consult with a medical provider for specific health concerns.
Estradiol Blood Test - More Information
The estradiol test, sometimes known as an E2 test or an estrogen lab test, measures the blood level of estradiol.
Estradiol (E2) is a steroid hormone that serves important roles in both women and men. E2 is made via several pathways in the body and uses cholesterol, and sometimes estrone, as a precursor. Estradiol is the most common type of estrogen (a larger class of sex hormones) found in the bodies of nonpregnant women and men. As one might expect, the blood level of estradiol will usually vary at different stages of life and, in women, during pregnancy.
In women of childbearing age, estradiol is primarily produced within the follicles of the ovaries. Otherwise, estradiol is also made in smaller quantities in the liver, fat, breast and other tissues. Along with progesterone, estradiol is an important hormone in the growth and maintenance of organs related to sex and fertility such as the uterus, breasts and fallopian tubes. More specifically, estradiol drives many of the changes in a woman's body during puberty and also impacts bone health, breast development and overall body morphology.
During a woman's menstrual cycle, estradiol plays various roles supporting the lining of the uterus and germ cells in the ovaries. Additionally, elevations in estradiol blood levels during the cycle lead to an increase in LH blood levels which ultimately results in ovulation. Estradiol also works synergistically with the hormone progesterone to thicken the endometrial lining in preparation for the implantation of an embryo. During pregnancy, estradiol levels although the most common estrogen found in a pregnant woman is usually estriol. Once out of childbearing years, estradiol continues to be important in regulating fat distribution and bone and joint health. In fact, estrogen deficiencies if post-menopausal women can result in significant bone loss.
In men, estradiol, while typically existing at lower levels, still has an important role. Estradiol helps maintain sperm cell health and does have a role in sexual function. Estradiol test levels are also monitored for men who are undergoing testosterone replacement therapy as this form of hormone replacement can cause the estradiol blood test levels to vary out of normal ranges.
Getting an estradiol test near you at a Quest Diagnostics lab is a relatively simple process as all standard lab locations will have the necessary equipment to perform an estradiol blood test. Once you place your order and select a lab location, you will need to get your blood drawn at the lab. Once your estradiol test results are ready, they will be released to you electronically. Interpreting an estradiol lab test report is not too difficult. As can be seen on the E2 sample report provided above, the estradiol blood level is reported as a number in the results column. The reference range for this blood test is also provided by the lab and, in this particular sample report, the estradiol result of 22 falls within the standard range. In specific contexts, one might expect the estradiol level to be above the reference range and these situations should be interpreted with the help of your medical provider.
This estradiol test uses an immunoassay lab methodology. For people who need a more sensitive estradiol test, please see the estradiol ultrasensitive test which uses the LC/MS/MS lab methodology.
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