Coombs Test FAQ
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DAT Blood Test - More Information
This Coombs test, also known as a direct Coombs blood test, DAT blood test, and a direct antiglobulin test (DAT), is a direct Coombs test.
The direct Coombs test is used to check for specific types of red blood cell destruction (hemolytic anemia) caused mistakenly by the immune system. In some people, red blood cells are destroyed because the immune system treats them as foreign cells. These red blood cells are treated this way because certain types of proteins bind to the outside of the red blood cells, triggering their destruction.
This direct Coombs test checks if the red blood cells have been abnormally coated by proteins from the immune system. This DAT blood test is considered positive if red blood cells are found to be coated. This Coombs blood test will be positive in cases of immune-mediated red cell destruction, a reaction from a blood transfusion reaction or after taking certain medications.
To get a direct Coombs test near you at Quest Diagnostics, simply order online and get tested at the lab. Once your Coombs test lab report is ready, it will be available for download. As can be seen on the sample Coombs lab test results above, the direct antiglobulin test result will be reported as a negative or positive.
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